| DAA2444 |
AMP-activated protein kinase; non-catalytic gamma-3 subunit decreases with age |
Molecular |
mesenchymal stem cell |
Human |
PRKAG3 |
20.1% Decrease DNA Methylation |
|
| DAA2434 |
nerve growth factor; beta polypeptide precursor decreases with age |
Molecular |
mesenchymal stem cell |
Human |
NGF |
22.5% Decrease DNA Methylation |
|
| DAA2450 |
casein kappa increases with age |
Molecular |
mesenchymal stem cell |
Human |
CSN3 |
16.3% Increase DNA Methylation |
|
| DAA2455 |
CD34 antigen isoform b decreases with age |
Molecular |
mesenchymal stem cell |
Human |
CD34 |
17.3% Decrease DNA Methylation |
|
| DAA2456 |
PDZ and LIM domain 2 isoform 3 increases with age |
Molecular |
mesenchymal stem cell |
Human |
PDLIM2 |
43.9% Increase DNA Methylation |
|
| DAA2454 |
chemokine (C-C motif) receptor 1 increases with age |
Molecular |
mesenchymal stem cell |
Human |
CCR1 |
31.2% Increase DNA Methylation |
|
| DAA2441 |
complement factor D preproprotein increases with age |
Molecular |
mesenchymal stem cell |
Human |
CFD |
22.2% Increase DNA Methylation |
|
| DAA2433 |
cyclin-dependent kinase inhibitor 2B isoform 2 decreases with age |
Molecular |
mesenchymal stem cell |
Human |
CDKN2B |
16.7% Decrease DNA Methylation |
|
| DAA2446 |
protein kinase C binding protein 1 isoform a increases with age |
Molecular |
mesenchymal stem cell |
Human |
ZMYND8 |
19.9% Increase DNA Methylation |
|
| DAA2447 |
protein kinase N1 isoform 2 increases with age |
Molecular |
mesenchymal stem cell |
Human |
PKN1 |
27.7% Increase DNA Methylation |
|
| DAA676 |
Proliferation rate of mesenchymal stem cells is reduced |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
| DAA675 |
Beta-galactosidase expression increases in mesenchymal stem cells |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
| DAA678 |
Capacity of mesenchymal stem cells to differentiate into osteoblasts may be decreased |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
| DAA2027 |
DNA damage acummulates in hematopoietic stem and progenitor cells |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
| DAA1073 |
Fewer cells and higher apoptosis |
Physiological |
bone marrow |
Human |
— |
— |
|
| DAA1991 |
Hematopoietic cells accumulate random mutations |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
| DAA2014 |
Microsatellite instability in hematopoietic stem cells and progenitor cells |
Physiological |
hematopoietic stem cells |
Human |
MLH1 |
— |
|
| DAA2013 |
Number and differentiation potential of adipose tissue-derived stem cells declines with age |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
| DAA934 |
Number of mature B cells leaving the bone marrow declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
| DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
| DAA2035 |
Alterations in frequency, developmental potential and gene expression profile in hematopoietic stem cells |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
| DAA677 |
Proportion of apoptotic cells may be increased |
Physiological |
mesenchymal stem cell |
Human |
TP53 |
— |
|
| DAA932 |
Renewal capacity declines |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
| DAA936 |
Volume of hematopoietic bone marrow decreases |
Physiological |
bone marrow |
Human |
— |
— |
|
| DAA1960 |
Adipocyte formation increases |
Physiological |
bone marrow |
Mouse |
— |
— |
|