| DAA2004 |
miR-128 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR128-1 |
— |
|
| DAA950 |
Immune response to Epstein-Barr virus decreases in cytomegalovirus positive individuals |
Physiological |
immune system |
Human |
— |
— |
|
| DAA2003 |
miR-107 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR107 |
— |
|
| DAA2012 |
miR-1538 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR1538 |
— |
|
| DAA2011 |
miR-496 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR496 |
— |
|
| DAA2007 |
miR-155 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR155 |
— |
|
| DAA965 |
Incidence of anergia increases |
Physiological |
immune system |
Human |
— |
— |
|
| DAA2034 |
Expression of WRN decreases |
Molecular |
blood, immune system |
Human |
WRN |
52.0% Decrease Gene Expression Level |
|
| DAA2008 |
miR-24 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR24-1 |
— |
|
| DAA2010 |
miR-221 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR221 |
— |
|
| DAA945 |
Thymus involution |
Physiological |
thymus |
Human |
— |
— |
|
| DAA948 |
Volume of perivascular space around thymus increases |
Physiological |
thymus |
Human |
— |
— |
|
| DAA1230 |
E-rosette-forming cells decrease |
Physiological |
thymus |
Human |
— |
— |
|
| DAA1229 |
Declining T-lymphocyte production in the thymus |
Physiological |
thymus |
Human |
— |
— |
|
| DAA954 |
Number of T cell progenitors declines |
Physiological |
T cell progenitor |
Human |
— |
— |
|
| DAA989 |
telomere shortening |
Molecular |
lymphocytes |
Human |
— |
— |
|
| DAA956 |
Proliferation is reduced |
Physiological |
lymphocytes |
Human |
— |
— |
|
| DAA934 |
Number of mature B cells leaving the bone marrow declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
| DAA939 |
Naive cell number increases and memory cells decrease |
Physiological |
B cell |
Human |
— |
— |
|
| DAA944 |
Less antibodies generated |
Physiological |
B cell |
Human |
— |
— |
|
| DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
| DAA940 |
B naive cells' susceptibility to apoptosis decreases |
Physiological |
memory B cell |
Human |
— |
— |
|
| DAA2563 |
Level of miR-19a decreases with age |
Molecular |
T cell |
Human |
MIR19A |
49.0% Decrease miRNA Level |
|
| DAA2559 |
Level of let-7f decreases with age |
Molecular |
T cell |
Human |
MIRLET7F1 |
65.6% Decrease miRNA Level |
|
| DAA961 |
Increased apoptosis associated with Fas and Fas-ligand expression |
Physiological |
T cell |
Human |
FAS |
— |
|