| DAA94 |
guanine nucleotide binding protein (G protein), gamma 12 |
Molecular |
brain |
Human |
GNG12 |
19.0% Increase Gene Expression Level |
|
| DAA940 |
B naive cells' susceptibility to apoptosis decreases |
Physiological |
memory B cell |
Human |
— |
— |
|
| DAA944 |
Less antibodies generated |
Physiological |
B cell |
Human |
— |
— |
|
| DAA945 |
Thymus involution |
Physiological |
thymus |
Human |
— |
— |
|
| DAA946 |
Thymic hormone levels decrease |
Physiological |
plasma |
Human |
— |
— |
|
| DAA948 |
Volume of perivascular space around thymus increases |
Physiological |
thymus |
Human |
— |
— |
|
| DAA949 |
Cytomegalovirus infection incidence increases |
Pathological |
immune system |
Human |
— |
— |
|
| DAA95 |
cell division cycle 2-like 2 (PITSLRE proteins) |
Molecular |
brain |
Human |
CDC2L2 |
27.0% Increase Gene Expression Level |
|
| DAA950 |
Immune response to Epstein-Barr virus decreases in cytomegalovirus positive individuals |
Physiological |
immune system |
Human |
— |
— |
|
| DAA952 |
Fewer CD4+ and CD8+ cells |
Physiological |
T cell |
Human |
— |
— |
|
| DAA953 |
Increase in cells that are both CD8+ and CD28-null |
Physiological |
T regulatory cell |
Human |
— |
— |
|
| DAA954 |
Number of T cell progenitors declines |
Physiological |
T cell progenitor |
Human |
— |
— |
|
| DAA955 |
Interleukin-7 production declines |
Physiological |
stromal cell |
Human |
IL7 |
— |
|
| DAA956 |
Proliferation is reduced |
Physiological |
lymphocytes |
Human |
— |
— |
|
| DAA959 |
telomere shortening |
Molecular |
naïve T cell |
Human |
— |
— |
|
| DAA96 |
G protein-coupled receptor, family C, group 5, member B |
Molecular |
brain |
Human |
GPRC5B |
10.0% Increase Gene Expression Level |
|
| DAA960 |
Receptor expression alterations |
Physiological |
grey matter |
Human |
— |
— |
|
| DAA961 |
Increased apoptosis associated with Fas and Fas-ligand expression |
Physiological |
T cell |
Human |
FAS |
— |
|
| DAA962 |
Interleukin-2 production in response to influenza vaccine declines |
Physiological |
T cell |
Human |
IL2 |
— |
|
| DAA963 |
Expansion into effector cells is reduced |
Physiological |
naïve T cell |
Human |
— |
— |
|
| DAA964 |
T-cell diversity declines |
Physiological |
T cell |
Human |
— |
— |
|
| DAA965 |
Incidence of anergia increases |
Physiological |
immune system |
Human |
— |
— |
|
| DAA966 |
Vaccination antibody response is impaired |
Physiological |
immune system |
Human |
— |
— |
|
| DAA968 |
Chronic inflammation increases |
Physiological |
blood, immune system |
Human |
— |
— |
|
| DAA968 |
Chronic inflammation increases |
Physiological |
blood, immune system |
Human |
— |
— |
|