Zic family member 1

Symbol

ZIC1 (may also be known as: None)

Organism

Human

Description

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
zic1 Danio rerio
Zic1 Mus musculus
Zic1 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006355 regulation of transcription, DNA-dependent biological_process
GO:0007389 pattern specification process biological_process
GO:0007420 brain development biological_process
GO:0007610 behavior biological_process
GO:0008589 regulation of smoothened signaling pathway biological_process
GO:0021510 spinal cord development biological_process
Show more GO terms