syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
Symbol
SNTB1
(may also be known as: None)
Organism
Human
Description
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| sntb1 | Danio rerio | |
| Sntb1 | Mus musculus | |
| Sntb1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006936 | muscle contraction | biological_process | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005856 | cytoskeleton | cellular_component | |
| GO:0016010 | dystrophin-associated glycoprotein complex | cellular_component | |
| GO:0030054 | cell junction | cellular_component | |
| GO:0042383 | sarcolemma | cellular_component | |
| GO:0045202 | synapse | cellular_component | |
| GO:0003779 | actin binding | molecular_function | |
| GO:0005515 | protein binding | molecular_function | |
| GO:0005516 | calmodulin binding | molecular_function | |
| GO:0030165 | PDZ domain binding | molecular_function | |