ryanodine receptor 3
Symbol
RYR3
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum followed by depolarization of T-tubules. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Orthologs
| Symbol | Species | |
|---|---|---|
| ryr3 | Danio rerio | |
| Ryr3 | Mus musculus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006811 | ion transport | biological_process | |
| GO:0006816 | calcium ion transport | biological_process | |
| GO:0006874 | cellular calcium ion homeostasis | biological_process | |
| GO:0006941 | striated muscle contraction | biological_process | |
| GO:0051289 | protein homotetramerization | biological_process | |
| GO:0055085 | transmembrane transport | biological_process | |
| GO:0070588 | calcium ion transmembrane transport | biological_process | |
| GO:0071277 | cellular response to calcium ion | biological_process | |
| GO:0071286 | cellular response to magnesium ion | biological_process | |
| GO:0071313 | cellular response to caffeine | biological_process | |
| GO:0071318 | cellular response to ATP | biological_process | |
| GO:0005792 | microsome | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0030314 | junctional membrane complex | cellular_component | |
| GO:0033017 | sarcoplasmic reticulum membrane | cellular_component | |
| GO:0004872 | receptor activity | molecular_function | |
| GO:0005216 | ion channel activity | molecular_function | |
| GO:0005219 | ryanodine-sensitive calcium-release channel activity | molecular_function | |
| GO:0005262 | calcium channel activity | molecular_function | |
| GO:0005509 | calcium ion binding | molecular_function | |
| GO:0005516 | calmodulin binding | molecular_function | |
| GO:0015278 | calcium-release channel activity | molecular_function | |