T-box 20
Symbol
TBX20
(may also be known as: None)
Organism
Human
Description
This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Orthologs
Symbol | Species | |
---|---|---|
mid | Drosophila melanogaster | |
tbx20 | Danio rerio | |
Tbx20 | Mus musculus | |
Tbx20 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
GO ID | GO Term | GO Category | |
---|---|---|---|
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | biological_process | |
GO:0001569 | patterning of blood vessels | biological_process | |
GO:0001706 | endoderm formation | biological_process | |
GO:0001764 | neuron migration | biological_process | |
GO:0001947 | heart looping | biological_process | |
GO:0003148 | outflow tract septum morphogenesis | biological_process | |
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