T-box 20

Symbol

TBX20 (may also be known as: None)

Organism

Human

Description

This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Orthologs

SymbolSpecies
mid Drosophila melanogaster
tbx20 Danio rerio
Tbx20 Mus musculus
Tbx20 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0000122 negative regulation of transcription from RNA polymerase II promoter biological_process
GO:0001569 patterning of blood vessels biological_process
GO:0001706 endoderm formation biological_process
GO:0001764 neuron migration biological_process
GO:0001947 heart looping biological_process
GO:0003148 outflow tract septum morphogenesis biological_process
Show more GO terms