POU class 4 homeobox 3
Symbol
POU4F3
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15. [provided by RefSeq, Mar 2009]
Orthologs
| Symbol | Species | |
|---|---|---|
| acj6 | Drosophila melanogaster | |
| pou4f3 | Danio rerio | |
| Pou4f3 | Mus musculus | |
| Pou4f3 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-dependent | biological_process | |
| GO:0006357 | regulation of transcription from RNA polymerase II promoter | biological_process | |
| GO:0007601 | visual perception | biological_process | |
| GO:0007605 | sensory perception of sound | biological_process | |
| GO:0021562 | vestibulocochlear nerve development | biological_process | |
| GO:0031290 | retinal ganglion cell axon guidance | biological_process | |
| GO:0042472 | inner ear morphogenesis | biological_process | |
| GO:0042491 | auditory receptor cell differentiation | biological_process | |
| GO:0048676 | axon extension involved in development | biological_process | |
| GO:0050885 | neuromuscular process controlling balance | biological_process | |
| GO:0051402 | neuron apoptosis | biological_process | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005730 | nucleolus | cellular_component | |
| GO:0003700 | sequence-specific DNA binding transcription factor activity | molecular_function | |
| GO:0043565 | sequence-specific DNA binding | molecular_function | |