POU class 4 homeobox 3

Symbol

POU4F3 (may also be known as: None)

Organism

Human

Description

This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15. [provided by RefSeq, Mar 2009]

Orthologs

Symbol	Species
acj6	Drosophila melanogaster
pou4f3	Danio rerio
Pou4f3	Mus musculus
Pou4f3	Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA2669	Hypermethylation of POU4F3 is positively correlated with age	Molecular	blood	Human	POU4F3	—

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GO Terms

GO ID	GO Term	GO Category
GO:0006355	regulation of transcription, DNA-dependent	biological_process
GO:0006357	regulation of transcription from RNA polymerase II promoter	biological_process
GO:0007601	visual perception	biological_process
GO:0007605	sensory perception of sound	biological_process
GO:0021562	vestibulocochlear nerve development	biological_process
GO:0031290	retinal ganglion cell axon guidance	biological_process
GO:0042472	inner ear morphogenesis	biological_process
GO:0042491	auditory receptor cell differentiation	biological_process
GO:0048676	axon extension involved in development	biological_process
GO:0050885	neuromuscular process controlling balance	biological_process
GO:0051402	neuron apoptosis	biological_process
GO:0005634	nucleus	cellular_component
GO:0005730	nucleolus	cellular_component
GO:0003700	sequence-specific DNA binding transcription factor activity	molecular_function
GO:0043565	sequence-specific DNA binding	molecular_function
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