NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
Symbol
NDUFS5
(may also be known as: None)
Organism
Human
Description
This gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 1, 4 and 17. [provided by RefSeq, May 2010]
Orthologs
| Symbol | Species | |
|---|---|---|
| nduf-5 | Caenorhabditis elegans | |
| ndufs5 | Danio rerio | |
| Ndufs5 | Mus musculus | |
| Ndufs5 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | biological_process | |
| GO:0006810 | transport | biological_process | |
| GO:0022904 | respiratory electron transport chain | biological_process | |
| GO:0032981 | mitochondrial respiratory chain complex I assembly | biological_process | |
| GO:0044281 | small molecule metabolic process | biological_process | |
| GO:0005739 | mitochondrion | cellular_component | |
| GO:0005743 | mitochondrial inner membrane | cellular_component | |
| GO:0005747 | mitochondrial respiratory chain complex I | cellular_component | |
| GO:0005758 | mitochondrial intermembrane space | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0070469 | respiratory chain | cellular_component | |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | molecular_function | |