fatty acid desaturase 3
Symbol
FADS3
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| Fads3 | Mus musculus | |
| Fads3 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2811 | Gene expression of FADS3 increases with age | Molecular | adipose tissue | Human | FADS3 | — |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006629 | lipid metabolic process | biological_process | |
| GO:0006633 | fatty acid biosynthetic process | biological_process | |
| GO:0006636 | unsaturated fatty acid biosynthetic process | biological_process | |
| GO:0006810 | transport | biological_process | |
| GO:0022900 | electron transport chain | biological_process | |
| GO:0055114 | oxidation-reduction process | biological_process | |
| GO:0005624 | membrane fraction | cellular_component | |
| GO:0005783 | endoplasmic reticulum | cellular_component | |
| GO:0005789 | endoplasmic reticulum membrane | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0003674 | molecular_function | molecular_function | |
| GO:0016491 | oxidoreductase activity | molecular_function | |
| GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water | molecular_function | |
| GO:0020037 | heme binding | molecular_function | |