biogenesis of lysosomal organelles complex-1, subunit 2


BLOC1S2 (may also be known as: None)




This gene encodes a protein with multiple functions. The encoded protein has been found in association with the centrosome, shown to co-localize with gamma-tubulin, and also found to be one of the proteins in the BLOC-1 complex which functions in the formation of lysosome-related organelles. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]


blos-2 Caenorhabditis elegans
blos2 Drosophila melanogaster
zgc:111974 Danio rerio
Bloc1s2 Mus musculus
Bloc1s2 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0007020 microtubule nucleation biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0032438 melanosome organization biological_process
GO:0042981 regulation of apoptotic process biological_process
GO:0045893 positive regulation of transcription, DNA-dependent biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter biological_process
GO:0060155 platelet dense granule organization biological_process
GO:0000930 gamma-tubulin complex cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005813 centrosome cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0031083 BLOC-1 complex cellular_component
GO:0055037 recycling endosome cellular_component
GO:0005515 protein binding molecular_function
GO:0008022 protein C-terminus binding molecular_function
GO:0043015 gamma-tubulin binding molecular_function