glycine receptor, alpha 1

Symbol

GLRA1 (may also be known as: None)

Organism

Human

Description

The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Orthologs

SymbolSpecies
glra1 Danio rerio
Glra1 Mus musculus
Glra1 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0001508 regulation of action potential biological_process
GO:0001964 startle response biological_process
GO:0002087 regulation of respiratory gaseous exchange by neurological system process biological_process
GO:0006811 ion transport biological_process
GO:0006821 chloride transport biological_process
GO:0006936 muscle contraction biological_process
Show more GO terms