glycine receptor, alpha 1
Symbol
GLRA1
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Orthologs
Symbol | Species | |
---|---|---|
glra1 | Danio rerio | |
Glra1 | Mus musculus | |
Glra1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
GO ID | GO Term | GO Category | |
---|---|---|---|
GO:0001508 | regulation of action potential | biological_process | |
GO:0001964 | startle response | biological_process | |
GO:0002087 | regulation of respiratory gaseous exchange by neurological system process | biological_process | |
GO:0006811 | ion transport | biological_process | |
GO:0006821 | chloride transport | biological_process | |
GO:0006936 | muscle contraction | biological_process | |
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