carbohydrate (chondroitin 4) sulfotransferase 13

Symbol

CHST13 (may also be known as: None)

Organism

Human

Description

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. [provided by RefSeq, Aug 2011]

Orthologs

SymbolSpecies
Chst13 Mus musculus
Chst13 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0016051 carbohydrate biosynthetic process biological_process
GO:0030206 chondroitin sulfate biosynthetic process biological_process
GO:0000139 Golgi membrane cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity molecular_function
GO:0008146 sulfotransferase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0047756 chondroitin 4-sulfotransferase activity molecular_function