carbohydrate (chondroitin 4) sulfotransferase 13

Symbol

CHST13 (may also be known as: None)

Organism

Human

Description

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. [provided by RefSeq, Aug 2011]

Orthologs

SymbolSpecies
Chst13 Mus musculus
Chst13 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2699 Hypomethylation of CHST13 is positively correlated with age Molecular blood Human CHST13 —

GO Terms

GO IDGO TermGO Category
GO:0016051 carbohydrate biosynthetic process biological_process
GO:0030206 chondroitin sulfate biosynthetic process biological_process
GO:0000139 Golgi membrane cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity molecular_function
GO:0008146 sulfotransferase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0047756 chondroitin 4-sulfotransferase activity molecular_function