ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

Symbol

AGAP1 (may also be known as: None)

Organism

Human

Description

This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Orthologs

SymbolSpecies
agap1 Danio rerio
Agap1 Mus musculus
Agap1 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0007264 small GTPase mediated signal transduction biological_process
GO:0015031 protein transport biological_process
GO:0032312 regulation of ARF GTPase activity biological_process
GO:0005622 intracellular cellular_component
GO:0005737 cytoplasm cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0005525 GTP binding molecular_function
GO:0008060 ARF GTPase activator activity molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0046872 metal ion binding molecular_function