ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Symbol
AGAP1
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Orthologs
| Symbol | Species | |
|---|---|---|
| agap1 | Danio rerio | |
| Agap1 | Mus musculus | |
| Agap1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0007264 | small GTPase mediated signal transduction | biological_process | |
| GO:0015031 | protein transport | biological_process | |
| GO:0032312 | regulation of ARF GTPase activity | biological_process | |
| GO:0005622 | intracellular | cellular_component | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0000166 | nucleotide binding | molecular_function | |
| GO:0005525 | GTP binding | molecular_function | |
| GO:0008060 | ARF GTPase activator activity | molecular_function | |
| GO:0008270 | zinc ion binding | molecular_function | |
| GO:0046872 | metal ion binding | molecular_function | |