insulin-like growth factor 2 mRNA binding protein 1

Symbol

IGF2BP1 (may also be known as: None)

Organism

Human

Description

This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Orthologs

SymbolSpecies
igf2bp1 Danio rerio
Igf2bp1 Mus musculus
Igf2bp1 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006403 RNA localization biological_process
GO:0010610 regulation of mRNA stability involved in response to stress biological_process
GO:0017148 negative regulation of translation biological_process
GO:0042035 regulation of cytokine biosynthetic process biological_process
GO:0070934 CRD-mediated mRNA stabilization biological_process
GO:0005634 nucleus cellular_component
Show more GO terms