insulin-like growth factor 2 mRNA binding protein 1
Symbol
IGF2BP1
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Orthologs
Symbol | Species | |
---|---|---|
igf2bp1 | Danio rerio | |
Igf2bp1 | Mus musculus | |
Igf2bp1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
GO ID | GO Term | GO Category | |
---|---|---|---|
GO:0006403 | RNA localization | biological_process | |
GO:0010610 | regulation of mRNA stability involved in response to stress | biological_process | |
GO:0017148 | negative regulation of translation | biological_process | |
GO:0042035 | regulation of cytokine biosynthetic process | biological_process | |
GO:0070934 | CRD-mediated mRNA stabilization | biological_process | |
GO:0005634 | nucleus | cellular_component | |
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