Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2335 major histocompatibility complex, class I-related increases with age Molecular hippocampus Human MR1 46.6% Increase Gene Expression Level
DAA2336 major histocompatibility complex, class I, C increases with age Molecular parietal lobe Human HLA-C 37.7% Increase Gene Expression Level
DAA2337 major histocompatibility complex, class I, E increases with age Molecular parietal lobe Human HLA-E 43.9% Increase Gene Expression Level
DAA2338 major histocompatibility complex, class I, E increases with age Molecular parietal lobe Human HLA-E 41.6% Increase Gene Expression Level
DAA2339 major histocompatibility complex, class I, E increases with age Molecular parietal lobe Human HLA-E 34.9% Increase Gene Expression Level
DAA2340 MHC class I polypeptide-related sequence B increases with age Molecular parietal lobe Human MICB 39.9% Increase Gene Expression Level
DAA2341 major histocompatibility complex, class I, B increases with age Molecular frontal lobe Human HLA-B 36.5% Increase Gene Expression Level
DAA2342 major histocompatibility complex, class I, C increases with age Molecular frontal lobe Human HLA-C 40.1% Increase Gene Expression Level
DAA2343 major histocompatibility complex, class I, E increases with age Molecular frontal lobe Human HLA-E 61.2% Increase Gene Expression Level
DAA2344 major histocompatibility complex, class I, E increases with age Molecular frontal lobe Human HLA-E 76.9% Increase Gene Expression Level
DAA2345 major histocompatibility complex, class I, E increases with age Molecular frontal lobe Human HLA-E 65.7% Increase Gene Expression Level
DAA2346 major histocompatibility complex, class I, F increases with age Molecular frontal lobe Human HLA-F 28.9% Increase Gene Expression Level
DAA2347 HLA-G histocompatibility antigen, class I, G increases with age Molecular frontal lobe Human HLA-G 28.4% Increase Gene Expression Level
DAA2348 MHC class I polypeptide-related sequence A increases with age Molecular frontal lobe Human MICA 37.9% Increase Gene Expression Level
DAA2349 major histocompatibility complex, class I-related increases with age Molecular frontal lobe Human MR1 22.4% Increase Gene Expression Level
DAA2350 major histocompatibility complex, class I-related increases with age Molecular frontal lobe Human MR1 32.2% Increase Gene Expression Level
DAA2351 Pannexin 2 decreases with age Molecular frontal lobe Human PANX2 8.1% Decrease Gene Expression Level
DAA2352 Pannexin 2 decreases with age Molecular hippocampus Human PANX2 19.1% Decrease Gene Expression Level
DAA2353 Pannexin 2 decreases with age Molecular temporal lobe Human PANX2 16.5% Decrease Gene Expression Level
DAA2354 major histocompatibility complex, class II, DR alpha increases with age Molecular temporal lobe Human HLA-DRA 150.4% Increase Gene Expression Level
DAA2355 major histocompatibility complex, class II, DP beta 1 increases with age Molecular hippocampus Human HLA-DPB1 160.5% Increase Gene Expression Level
DAA2356 major histocompatibility complex, class II, DP beta 1 increases with age Molecular hippocampus Human HLA-DPB1 13.2% Increase Gene Expression Level
DAA2357 major histocompatibility complex, class II, DQ beta 1 increases with age Molecular hippocampus Human HLA-DQB1 106.0% Increase Gene Expression Level
DAA2358 major histocompatibility complex, class II, DQ beta 1 increases with age Molecular hippocampus Human HLA-DQB1 135.4% Increase Gene Expression Level
DAA2359 major histocompatibility complex, class II, DR alpha increases with age Molecular hippocampus Human HLA-DRA 324.5% Increase Gene Expression Level