Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2310 major histocompatibility complex, class II, DM alpha increases with age Molecular temporal lobe Human HLA-DMA 110.6% Increase Gene Expression Level
DAA2311 major histocompatibility complex, class II, DR alpha increases with age Molecular temporal lobe Human HLA-DRA 146.7% Increase Gene Expression Level
DAA2312 major histocompatibility complex, class II, DM alpha increases with age Molecular hippocampus Human HLA-DMA 221.5% Increase Gene Expression Level
DAA2313 major histocompatibility complex, class II, DM beta increases with age Molecular hippocampus Human HLA-DMB 90.5% Increase Gene Expression Level
DAA2314 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular hippocampus Human HLA-DPA1 210.3% Increase Gene Expression Level
DAA2315 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular hippocampus Human HLA-DPA1 262.9% Increase Gene Expression Level
DAA2316 Major histocompatibility complex, class II, DP alpha 1 increases with age Molecular hippocampus Human HLA-DPA1 153.2% Increase Gene Expression Level
DAA2317 major histocompatibility complex, class II, DR alpha increases with age Molecular hippocampus Human HLA-DRA 317.7% Increase Gene Expression Level
DAA2318 major histocompatibility complex, class II, DM alpha increases with age Molecular parietal lobe Human HLA-DMA 169.9% Increase Gene Expression Level
DAA2319 major histocompatibility complex, class II, DM beta increases with age Molecular parietal lobe Human HLA-DMB 57.0% Increase Gene Expression Level
DAA2320 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular parietal lobe Human HLA-DPA1 124.3% Increase Gene Expression Level
DAA2321 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular parietal lobe Human HLA-DPA1 169.0% Increase Gene Expression Level
DAA2322 Major histocompatibility complex, class II, DP alpha 1 increases with age Molecular parietal lobe Human HLA-DPA1 35.8% Increase Gene Expression Level
DAA2323 major histocompatibility complex, class II, DR alpha increases with age Molecular parietal lobe Human HLA-DRA 241.7% Increase Gene Expression Level
DAA2324 major histocompatibility complex, class II, DM alpha increases with age Molecular frontal lobe Human HLA-DMA 115.5% Increase Gene Expression Level
DAA2325 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular frontal lobe Human HLA-DPA1 97.1% Increase Gene Expression Level
DAA2326 major histocompatibility complex, class II, DR alpha increases with age Molecular frontal lobe Human HLA-DRA 146.8% Increase Gene Expression Level
DAA2327 major histocompatibility complex, class I, B increases with age Molecular hippocampus Human HLA-B 35.0% Increase Gene Expression Level
DAA2328 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 32.6% Increase Gene Expression Level
DAA2329 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 76.6% Increase Gene Expression Level
DAA2330 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 58.3% Increase Gene Expression Level
DAA2331 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 39.2% Increase Gene Expression Level
DAA2332 HLA-G histocompatibility antigen, class I, G increases with age Molecular hippocampus Human HLA-G 30.6% Increase Gene Expression Level
DAA2333 HLA-G histocompatibility antigen, class I, G increases with age Molecular hippocampus Human HLA-G 30.5% Increase Gene Expression Level
DAA2334 HLA-G histocompatibility antigen, class I, G increases with age Molecular hippocampus Human HLA-G 26.0% Increase Gene Expression Level