Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2330 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 58.3% Increase Gene Expression Level
DAA2339 major histocompatibility complex, class I, E increases with age Molecular parietal lobe Human HLA-E 34.9% Increase Gene Expression Level
DAA2331 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 39.2% Increase Gene Expression Level
DAA2344 major histocompatibility complex, class I, E increases with age Molecular frontal lobe Human HLA-E 76.9% Increase Gene Expression Level
DAA2343 major histocompatibility complex, class I, E increases with age Molecular frontal lobe Human HLA-E 61.2% Increase Gene Expression Level
DAA2345 major histocompatibility complex, class I, E increases with age Molecular frontal lobe Human HLA-E 65.7% Increase Gene Expression Level
DAA2338 major histocompatibility complex, class I, E increases with age Molecular parietal lobe Human HLA-E 41.6% Increase Gene Expression Level
DAA2337 major histocompatibility complex, class I, E increases with age Molecular parietal lobe Human HLA-E 43.9% Increase Gene Expression Level
DAA2329 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 76.6% Increase Gene Expression Level
DAA2346 major histocompatibility complex, class I, F increases with age Molecular frontal lobe Human HLA-F 28.9% Increase Gene Expression Level
DAA2332 HLA-G histocompatibility antigen, class I, G increases with age Molecular hippocampus Human HLA-G 30.6% Increase Gene Expression Level
DAA2334 HLA-G histocompatibility antigen, class I, G increases with age Molecular hippocampus Human HLA-G 26.0% Increase Gene Expression Level
DAA2347 HLA-G histocompatibility antigen, class I, G increases with age Molecular frontal lobe Human HLA-G 28.4% Increase Gene Expression Level
DAA2333 HLA-G histocompatibility antigen, class I, G increases with age Molecular hippocampus Human HLA-G 30.5% Increase Gene Expression Level
DAA2260 interleukin 18 (interferon-gamma-inducing factor) increases with age Molecular parietal lobe Human IL18 56.7% Increase Gene Expression Level
DAA2251 interleukin 18 (interferon-gamma-inducing factor) increases with age Molecular hippocampus Human IL18 68.9% Increase Gene Expression Level
DAA2348 MHC class I polypeptide-related sequence A increases with age Molecular frontal lobe Human MICA 37.9% Increase Gene Expression Level
DAA2165 MHC class I polypeptide-related sequence A increases with age Molecular frontal lobe Human MICA 39.5% Increase Gene Expression Level
DAA2340 MHC class I polypeptide-related sequence B increases with age Molecular parietal lobe Human MICB 39.9% Increase Gene Expression Level
DAA2350 major histocompatibility complex, class I-related increases with age Molecular frontal lobe Human MR1 32.2% Increase Gene Expression Level
DAA2349 major histocompatibility complex, class I-related increases with age Molecular frontal lobe Human MR1 22.4% Increase Gene Expression Level
DAA2335 major histocompatibility complex, class I-related increases with age Molecular hippocampus Human MR1 46.6% Increase Gene Expression Level
DAA2216 myeloid differentiation primary response gene (88) increases with age Molecular hippocampus Human MYD88 59.3% Increase Gene Expression Level
DAA2230 myeloid differentiation primary response gene (88) increases with age Molecular parietal lobe Human MYD88 54.8% Increase Gene Expression Level
DAA2242 myeloid differentiation primary response gene (88) increases with age Molecular frontal lobe Human MYD88 58.7% Increase Gene Expression Level