Sharma et al. (2009) "The aging immune system and its relationship to the development of chronic obstructive pulmonary disease." Proc Am Thorac Soc 6(7):573-580 (PubMed) (13 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA974 Chemotaxis is reduced Physiological neutrophil, dendritic cell Human — —
DAA821 Chronic obstructive pulmonary disease incidence increases Pathological lung Human — —
DAA952 Fewer CD4+ and CD8+ cells Physiological T cell Human — —
DAA953 Increase in cells that are both CD8+ and CD28-null Physiological T regulatory cell Human — —
DAA975 Infiltration at injury site is reduced Physiological neutrophil Human — —
DAA955 Interleukin-7 production declines Physiological stromal cell Human IL7 —
DAA944 Less antibodies generated Physiological B cell Human — —
DAA954 Number of T cell progenitors declines Physiological T cell progenitor Human — —
DAA956 Proliferation is reduced Physiological lymphocytes Human — —
DAA960 Receptor expression alterations Physiological grey matter Human — —
DAA822 Small airway obstruction Pathological lung Human — —
DAA964 T-cell diversity declines Physiological T cell Human — —
DAA936 Volume of hematopoietic bone marrow decreases Physiological bone marrow Human — —