Lu et al. (2004) "Gene regulation and DNA damage in the ageing human brain." Nature 429(6994):883-891 (PubMed) (255 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA189 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Molecular brain Human PSMD8 8.0% Decrease Gene Expression Level
DAA173 protein inhibitor of activated STAT, 2 Molecular brain Human PIAS2 10.0% Decrease Gene Expression Level
DAA174 protein inhibitor of activated STAT, 3 Molecular brain Human PIAS3 10.0% Increase Gene Expression Level
DAA186 protein kinase C, beta Molecular brain Human PRKCB 11.0% Decrease Gene Expression Level
DAA187 protein kinase C, gamma Molecular brain Human PRKCG 12.0% Decrease Gene Expression Level
DAA188 protein kinase C, zeta Molecular brain Human PRKCZ 12.0% Decrease Gene Expression Level
DAA167 protein-L-isoaspartate (D-aspartate) O-methyltransferase Molecular brain Human PCMT1 12.0% Decrease Gene Expression Level
DAA182 protein phosphatase 1E (PP2C domain containing) Molecular brain Human PPM1E 17.0% Decrease Gene Expression Level
DAA183 protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform Molecular brain Human PPP2R1A 6.0% Decrease Gene Expression Level
DAA184 protein phosphatase 5, catalytic subunit Molecular brain Human PPP5C 7.0% Decrease Gene Expression Level
DAA190 protein tyrosine phosphatase, receptor type, E Molecular brain Human PTPRE 39.0% Decrease Gene Expression Level
DAA192 quaking homolog, KH domain RNA binding (mouse) Molecular brain Human QKI 8.0% Increase Gene Expression Level
DAA193 RAB2A, member RAS oncogene family Molecular brain Human RAB2A 11.0% Decrease Gene Expression Level
DAA194 RAB3A, member RAS oncogene family Molecular brain Human RAB3A 11.0% Decrease Gene Expression Level
DAA203 radixin Molecular brain Human RDX 13.0% Increase Gene Expression Level
DAA197 RAP2A, member of RAS oncogene family Molecular brain Human RAP2A 28.0% Decrease Gene Expression Level
DAA200 Ras association (RalGDS/AF-6) domain family member 2 Molecular brain Human RASSF2 18.0% Increase Gene Expression Level
DAA199 Ras protein-specific guanine nucleotide-releasing factor 1 Molecular brain Human RASGRF1 22.0% Decrease Gene Expression Level
DAA196 receptor (G protein-coupled) activity modifying protein 1 Molecular brain Human RAMP1 16.0% Increase Gene Expression Level
DAA206 regucalcin (senescence marker protein-30) Molecular brain Human RGN 15.0% Increase Gene Expression Level
DAA207 regulator of G-protein signaling 20 Molecular brain Human RGS20 25.0% Increase Gene Expression Level
DAA208 regulator of G-protein signaling 4 Molecular brain Human RGS4 16.0% Decrease Gene Expression Level
DAA204 replication factor C (activator 1) 5, 36.5kDa Molecular brain Human RFC5 7.0% Decrease Gene Expression Level
DAA213 reticulon 1 Molecular brain Human RTN1 8.0% Decrease Gene Expression Level
DAA214 reticulon 4 Molecular brain Human RTN4 8.0% Decrease Gene Expression Level