All physiological changes (343)

Identifier Name Data Tissues Organism Actions
DAA2595 Frequency of somatic mitochondrial mutations increases with age — brain Human
DAA2596 Frequency of mitochondrial DNA deletions increases with age — brain Human
DAA2597 Mitochondrial DNA content in non-centenerians decreases with age — blood Human
DAA2598 Renewal rate of cardiomyocytes decreases with age — heart Human
DAA2599 Telomere shortening — adipose tissue, skeletal muscle, skin, leukocyte Human
DAA2600 Chromosome deletions, duplications, and gene conversion events accumulate with age — colon Human
DAA642 Muscle atrophy (sarcopenia) — skeletal muscle Human
DAA643 Muscle fiber energy metabolism declines — skeletal muscle Human
DAA644 Tendons' ability to elongate decreases — tendon Human
DAA645 Bone remodeling decreases — bone Human
DAA646 Osteoporosis: progressive loss of bone strength — bone Human
DAA647 Bone resorption increases for cortical bone — bone Human
DAA648 Bone mass decreases — bone Human
DAA649 Bone mineral density in cortical ulna decreases — ulna Human
DAA650 Bone density of total hip and femoral neck decreases — bone Human
DAA651 Bone porosity increases — bone Human
DAA652 Mineralization of bone tissue increases — bone Human
DAA653 Bone becomes more brittle, less flexible — bone Human
DAA654 Fractures are cleaner — bone Human
DAA656 Synovial fluid alterations — synovium Human
DAA658 Cartilage color changes — cartilage Human
DAA659 Cell number decreases in cartilage — cartilage Human
DAA660 Cartilage joint surface cracks and frays — cartilage Human
DAA661 Cartilage matrix synthesis to degradation ratio decreases — cartilage Human
DAA662 Fibril types in cartilage matrix are altered — cartilage Human