DAA721 |
Neurofibrillary tangles and Lewy bodies in neurons |
Physiological |
brain |
Human |
— |
— |
|
DAA780 |
Medial temporal activation during encoding and retrieval of memory is reduced |
Physiological |
brain |
Human |
— |
— |
|
DAA723 |
Accumulation of extracellular neuritic plaques |
Physiological |
brain |
Human |
— |
— |
|
DAA1984 |
Layer-specific dendritic regression of pyramidal cells |
Physiological |
prefrontal cortex |
Human |
— |
— |
|
DAA725 |
Leukoaraiosis |
Physiological |
white matter |
Human |
— |
— |
|
DAA714 |
Neuronal soma shrinks in size |
Physiological |
brain |
Human |
— |
— |
|
DAA733 |
Neurotransmitter and neuro receptor concentrations are altered |
Physiological |
brain |
Human |
— |
— |
|
DAA735 |
Localized increases and decreases in synaptic transmission |
Physiological |
brain |
Human |
— |
— |
|
DAA741 |
Cerebral blood flow and glucose utilization are reduced |
Physiological |
brain |
Human |
— |
— |
|
DAA738 |
Cerebral spinal fluid amount increases |
Physiological |
brain |
Human |
— |
— |
|
DAA718 |
Synaptic density slightly decreases at advanced ages |
Physiological |
frontal lobe |
Human |
— |
— |
|
DAA788 |
Viscoelastic modulus of brain tissue decreases |
Physiological |
brain |
Human |
— |
— |
|
DAA1948 |
Neurogenesis is reduced |
Physiological |
brain |
Mouse |
— |
— |
|
DAA779 |
Prefrontal cortex activation during learning is reduced |
Physiological |
brain |
Human |
— |
— |
|
DAA1980 |
Reaction time for a visually paced simple motor task increases with age |
Physiological |
brain |
Human |
— |
— |
|
DAA732 |
Glial cell number |
Physiological |
cerebral cortex |
Human |
— |
— |
|
DAA724 |
Global neuron loss |
Physiological |
cerebral cortex |
Human |
— |
— |
|
DAA730 |
White matter volume decreases |
Physiological |
white matter |
Human |
— |
— |
|
DAA739 |
Degeneration of dopamine neurons and receptors |
Physiological |
brain |
Human |
— |
— |
|
DAA726 |
Demyelination |
Physiological |
white matter |
Human |
— |
— |
|
DAA717 |
Dendrite regression, reduction in dendrite length |
Physiological |
brain |
Human |
— |
— |
|
DAA764 |
Depolarization of mitochondria |
Physiological |
brain |
Human |
— |
— |
|
DAA727 |
Axon loss |
Physiological |
white matter |
Human |
— |
— |
|
DAA1996 |
Beta-amyloid protein deposition increases |
Physiological |
brain |
Human |
APP |
— |
|
DAA728 |
Brain matter volume declines |
Physiological |
brain |
Human |
— |
— |
|