| DAA1076 |
Progressive liquefaction |
Physiological |
vitreous humor |
Human |
— |
— |
|
| DAA2033 |
Alterations in structural proteins and cell membranes in the lenses |
Physiological |
lens |
Human |
— |
— |
|
| DAA2031 |
Altered concentration of sodium, potassium and calcium |
Physiological |
lens |
Human |
— |
— |
|
| DAA2029 |
Color of lenses increases |
Physiological |
lens |
Human |
— |
— |
|
| DAA2030 |
Transmission of visible light through eye lenses decreases |
Physiological |
lens |
Human |
— |
— |
|
| DAA2028 |
Eye lenses become much stiffer |
Physiological |
lens |
Human |
— |
— |
|
| DAA2032 |
The ratio of free to bound water increases |
Physiological |
lens |
Human |
— |
— |
|
| DAA1978 |
Age differences in classical conditioning of the eyelid response |
Physiological |
eyelid |
Human |
— |
— |
|
| DAA2583 |
Vision loss |
Physiological |
visual apparatus |
Human |
— |
— |
|
| DAA737 |
Permeability increases with age |
Physiological |
blood brain barrier |
Human |
— |
— |
|
| DAA729 |
Gray matter volume decreases |
Physiological |
grey matter |
Human |
— |
— |
|
| DAA960 |
Receptor expression alterations |
Physiological |
grey matter |
Human |
— |
— |
|
| DAA730 |
White matter volume decreases |
Physiological |
white matter |
Human |
— |
— |
|
| DAA726 |
Demyelination |
Physiological |
white matter |
Human |
— |
— |
|
| DAA727 |
Axon loss |
Physiological |
white matter |
Human |
— |
— |
|
| DAA725 |
Leukoaraiosis |
Physiological |
white matter |
Human |
— |
— |
|
| DAA731 |
Mean diffusivity increases and water diffusion anisotropy decreases |
Physiological |
corpus callosum, white matter |
Human |
— |
— |
|
| DAA731 |
Mean diffusivity increases and water diffusion anisotropy decreases |
Physiological |
corpus callosum, white matter |
Human |
— |
— |
|
| DAA2026 |
Mutations in mitochondrial DNA accumulate |
Physiological |
heart, kidney, skeletal muscle, cerebral cortex, cerebellum |
Human |
— |
— |
|
| DAA722 |
Accumulation of neuromelanin in dopaminergic nigral neurons |
Physiological |
substantia nigra |
Human |
— |
— |
|
| DAA1981 |
Selective increase in oxidative damage and decrease in antioxidant function during aging in the substantia nigra |
Physiological |
substantia nigra |
Human |
— |
— |
|
| DAA743 |
Sensitivity of HPA axis is impaired |
Physiological |
pituitary gland, adrenal gland, hypothalamus |
Human |
— |
— |
|
| DAA2036 |
Neural stem cell pool declines |
Physiological |
hippocampus |
Mouse |
— |
— |
|
| DAA1984 |
Layer-specific dendritic regression of pyramidal cells |
Physiological |
prefrontal cortex |
Human |
— |
— |
|
| DAA718 |
Synaptic density slightly decreases at advanced ages |
Physiological |
frontal lobe |
Human |
— |
— |
|