DAA2010 |
miR-221 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR221 |
— |
|
DAA2008 |
miR-24 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR24-1 |
— |
|
DAA2009 |
miR-24 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR24-2 |
— |
|
DAA2011 |
miR-496 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR496 |
— |
|
DAA939 |
Naive cell number increases and memory cells decrease |
Physiological |
B cell |
Human |
— |
— |
|
DAA934 |
Number of mature B cells leaving the bone marrow declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA954 |
Number of T cell progenitors declines |
Physiological |
T cell progenitor |
Human |
— |
— |
|
DAA980 |
Phagocytosis activity decreased in response to opsonized targets |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA981 |
Phagocytosis activity unchanged in response to unopsonized targets |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA956 |
Proliferation is reduced |
Physiological |
lymphocytes |
Human |
— |
— |
|
DAA977 |
ROS production in response to stimuli unchanged |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA700 |
Shift in reduced:oxidized glutathione ratio in favour of oxidized gluthione |
Physiological |
blood, lymphocytes |
Mouse |
— |
— |
|
DAA984 |
Spontaneous production of superoxide decreased |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA964 |
T-cell diversity declines |
Physiological |
T cell |
Human |
— |
— |
|
DAA989 |
telomere shortening |
Molecular |
lymphocytes |
Human |
— |
— |
|
DAA1986 |
telomere shortening |
Molecular |
leukocyte |
Human |
— |
— |
|
DAA959 |
telomere shortening |
Molecular |
naïve T cell |
Human |
— |
— |
|
DAA2599 |
Telomere shortening |
Physiological |
adipose tissue, skeletal muscle, skin, leukocyte |
Human |
— |
— |
|
DAA945 |
Thymus involution |
Physiological |
thymus |
Human |
— |
— |
|
DAA966 |
Vaccination antibody response is impaired |
Physiological |
immune system |
Human |
— |
— |
|
DAA1947 |
Vitamin C levels decrease |
Physiological |
blood, T cell |
Mouse |
— |
— |
|
DAA948 |
Volume of perivascular space around thymus increases |
Physiological |
thymus |
Human |
— |
— |
|