THO complex 1

Symbol

THOC1 (may also be known as: None)

Organism

Human

Description

HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010]

Orthologs

Symbol	Species
thoc-1	Caenorhabditis elegans
Hpr1	Drosophila melanogaster
thoc1	Danio rerio
Thoc1	Mus musculus
SPCP25A2.03	Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA3588	Gene expression of THOC1 increases with age	Molecular	skin	Human	THOC1	—

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GO Terms

GO ID	GO Term	GO Category
GO:0006396	RNA processing	biological_process
GO:0006397	mRNA processing	biological_process
GO:0006406	mRNA export from nucleus	biological_process
GO:0006810	transport	biological_process
GO:0006915	apoptotic process	biological_process
GO:0007165	signal transduction	biological_process
GO:0008380	RNA splicing	biological_process
GO:0032784	regulation of transcription elongation, DNA-dependent	biological_process
GO:0046784	intronless viral mRNA export from host nucleus	biological_process
GO:0000346	transcription export complex	cellular_component
GO:0000347	THO complex	cellular_component
GO:0000445	THO complex part of transcription export complex	cellular_component
GO:0005634	nucleus	cellular_component
GO:0005654	nucleoplasm	cellular_component
GO:0005730	nucleolus	cellular_component
GO:0005737	cytoplasm	cellular_component
GO:0016363	nuclear matrix	cellular_component
GO:0016607	nuclear speck	cellular_component
GO:0003677	DNA binding	molecular_function
GO:0003723	RNA binding	molecular_function
GO:0005515	protein binding	molecular_function
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