mannose-P-dolichol utilization defect 1


MPDU1 (may also be known as: None)




This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols. Mutations in this gene result in congenital disorder of glycosylation type If. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]


F38E1.9 Caenorhabditis elegans
CG3792 Drosophila melanogaster
mpdu1b Danio rerio
Mpdu1 Mus musculus
Mpdu1 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006457 protein folding biological_process
GO:0006488 dolichol-linked oligosaccharide biosynthetic process biological_process
GO:0006810 transport biological_process
GO:0009312 oligosaccharide biosynthetic process biological_process
GO:0005739 mitochondrion cellular_component
GO:0005783 endoplasmic reticulum cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component