dehydrogenase/reductase (SDR family) member 3
Symbol
DHRS3
(may also be known as: None)
Organism
Human
Description
Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]
Orthologs
| Symbol | Species | |
|---|---|---|
| dhrs3a | Danio rerio | |
| Dhrs3 | Mus musculus | |
| Dhrs3 | Rattus norvegicus | |
| TDA5 | Saccharomyces cerevisiae |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2388 | dehydrogenase/reductase (SDR family) member 3 decreases with age | Molecular | dermis | Human | DHRS3 | 15.8% Decrease DNA Methylation | |
| DAA2437 | dehydrogenase/reductase (SDR family) member 3 decreases with age | Molecular | mesenchymal stem cell | Human | DHRS3 | 18.6% Decrease DNA Methylation |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0007601 | visual perception | biological_process | |
| GO:0042572 | retinol metabolic process | biological_process | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0000166 | nucleotide binding | molecular_function | |
| GO:0009055 | electron carrier activity | molecular_function | |
| GO:0016491 | oxidoreductase activity | molecular_function | |
| GO:0052650 | NADP-retinol dehydrogenase activity | molecular_function | |