adaptor-related protein complex 1, sigma 2 subunit

Symbol

AP1S2 (may also be known as: None)

Organism

Human

Description

Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]

Orthologs

SymbolSpecies
ap1s2 Danio rerio
Ap1s2 Mus musculus
Ap1s2 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006886 intracellular protein transport biological_process
GO:0006892 post-Golgi vesicle-mediated transport biological_process
GO:0006897 endocytosis biological_process
GO:0016032 viral reproduction biological_process
GO:0016044 cellular membrane organization biological_process
GO:0016192 vesicle-mediated transport biological_process
Show more GO terms