microfibrillar associated protein 5
Symbol
MFAP5
(may also be known as: None)
Organism
Human
Description
This gene encodes a 25-kD microfibril-associated glycoprotein which is rich in serine and threonine residues. It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs. The structural differences suggest that this encoded protein has some functions that are distinct from those of MFAP2. [provided by RefSeq, Jul 2008]
Orthologs
Symbol | Species | |
---|---|---|
Mfap5 | Mus musculus | |
Mfap5 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
---|---|---|---|---|---|---|---|
DAA2400 | microfibrillar associated protein 5 decreases with age | Molecular | dermis | Human | MFAP5 | 15.0% Decrease DNA Methylation | |
DAA2449 | microfibrillar associated protein 5 decreases with age | Molecular | mesenchymal stem cell | Human | MFAP5 | 46.4% Decrease DNA Methylation |
GO Terms
GO ID | GO Term | GO Category |
---|---|---|
GO:0001527 | microfibril | cellular_component |
GO:0005576 | extracellular region | cellular_component |
GO:0005578 | proteinaceous extracellular matrix | cellular_component |
GO:0005201 | extracellular matrix structural constituent | molecular_function |