TAZ (may also be known as: None)




This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known. [provided by RefSeq, Jul 2008]


acl-3 Caenorhabditis elegans
Taz Drosophila melanogaster
taz Danio rerio
Taz Mus musculus
Taz Rattus norvegicus
TAZ1 Saccharomyces cerevisiae

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006936 muscle contraction biological_process
GO:0007507 heart development biological_process
GO:0007519 skeletal muscle tissue development biological_process
GO:0008152 metabolic process biological_process
GO:0030097 hemopoiesis biological_process
GO:0032049 cardiolipin biosynthetic process biological_process
GO:0032981 mitochondrial respiratory chain complex I assembly biological_process
GO:0042407 cristae formation biological_process
GO:0042775 mitochondrial ATP synthesis coupled electron transport biological_process
GO:0048738 cardiac muscle tissue development biological_process
GO:0060048 cardiac muscle contraction biological_process
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005886 plasma membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0005515 protein binding molecular_function
GO:0016746 transferase activity, transferring acyl groups molecular_function
GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity molecular_function