mitogen-activated protein kinase 1

Symbol

MAPK1 (may also be known as: ERK, ERK2,)

Organism

Human

Orthologs

Symbol	Species
mapk1	Danio rerio
Mapk1	Mus musculus
Mapk1	Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA131	mitogen-activated protein kinase 1	Molecular	brain	Human	MAPK1	17.0% Decrease Gene Expression Level

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GO Terms

GO ID	GO Term	GO Category
GO:0000165	MAPKKK cascade	biological_process
GO:0000186	activation of MAPKK activity	biological_process
GO:0000187	activation of MAPK activity	biological_process
GO:0000189	MAPK import into nucleus	biological_process
GO:0002224	toll-like receptor signaling pathway	biological_process
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	biological_process
GO:0002756	MyD88-independent toll-like receptor signaling pathway	biological_process
GO:0006915	apoptotic process	biological_process
GO:0006917	induction of apoptosis	biological_process
GO:0006935	chemotaxis	biological_process
GO:0006950	response to stress	biological_process
GO:0006974	response to DNA damage stimulus	biological_process
GO:0007049	cell cycle	biological_process
GO:0007165	signal transduction	biological_process
GO:0007173	epidermal growth factor receptor signaling pathway	biological_process
GO:0007264	small GTPase mediated signal transduction	biological_process
GO:0007265	Ras protein signal transduction	biological_process
GO:0007268	synaptic transmission	biological_process
GO:0007411	axon guidance	biological_process
GO:0007596	blood coagulation	biological_process
GO:0008063	Toll signaling pathway	biological_process
GO:0008284	positive regulation of cell proliferation	biological_process
GO:0008286	insulin receptor signaling pathway	biological_process
GO:0008543	fibroblast growth factor receptor signaling pathway	biological_process
GO:0009636	response to toxin	biological_process
GO:0009887	organ morphogenesis	biological_process
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	biological_process
GO:0018105	peptidyl-serine phosphorylation	biological_process
GO:0019233	sensory perception of pain	biological_process
GO:0019858	cytosine metabolic process	biological_process
GO:0030168	platelet activation	biological_process
GO:0030335	positive regulation of cell migration	biological_process
GO:0031663	lipopolysaccharide-mediated signaling pathway	biological_process
GO:0032496	response to lipopolysaccharide	biological_process
GO:0032872	regulation of stress-activated MAPK cascade	biological_process
GO:0033598	mammary gland epithelial cell proliferation	biological_process
GO:0034130	toll-like receptor 1 signaling pathway	biological_process
GO:0034134	toll-like receptor 2 signaling pathway	biological_process
GO:0034138	toll-like receptor 3 signaling pathway	biological_process
GO:0034142	toll-like receptor 4 signaling pathway	biological_process
GO:0035556	intracellular signal transduction	biological_process
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	biological_process
GO:0043330	response to exogenous dsRNA	biological_process
GO:0043627	response to estrogen stimulus	biological_process
GO:0044419	interspecies interaction between organisms	biological_process
GO:0045087	innate immune response	biological_process
GO:0045596	negative regulation of cell differentiation	biological_process
GO:0045727	positive regulation of translation	biological_process
GO:0045893	positive regulation of transcription, DNA-dependent	biological_process
GO:0048011	nerve growth factor receptor signaling pathway	biological_process
GO:0050852	T cell receptor signaling pathway	biological_process
GO:0050853	B cell receptor signaling pathway	biological_process
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	biological_process
GO:0051403	stress-activated MAPK cascade	biological_process
GO:0051493	regulation of cytoskeleton organization	biological_process
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	biological_process
GO:0060716	labyrinthine layer blood vessel development	biological_process
GO:0070371	ERK1 and ERK2 cascade	biological_process
GO:0072584	caveolin-mediated endocytosis	biological_process
GO:0090170	regulation of Golgi inheritance	biological_process
GO:2000641	regulation of early endosome to late endosome transport	biological_process
GO:0005625	soluble fraction	cellular_component
GO:0005626	insoluble fraction	cellular_component
GO:0005634	nucleus	cellular_component
GO:0005654	nucleoplasm	cellular_component
GO:0005737	cytoplasm	cellular_component
GO:0005739	mitochondrion	cellular_component
GO:0005769	early endosome	cellular_component
GO:0005770	late endosome	cellular_component
GO:0005794	Golgi apparatus	cellular_component
GO:0005815	microtubule organizing center	cellular_component
GO:0005829	cytosol	cellular_component
GO:0005856	cytoskeleton	cellular_component
GO:0005901	caveola	cellular_component
GO:0005925	focal adhesion	cellular_component
GO:0031143	pseudopodium	cellular_component
GO:0032839	dendrite cytoplasm	cellular_component
GO:0033267	axon part	cellular_component
GO:0043204	perikaryon	cellular_component
GO:0043234	protein complex	cellular_component
GO:0000166	nucleotide binding	molecular_function
GO:0001784	phosphotyrosine binding	molecular_function
GO:0003677	DNA binding	molecular_function
GO:0004674	protein serine/threonine kinase activity	molecular_function
GO:0004707	MAP kinase activity	molecular_function
GO:0005515	protein binding	molecular_function
GO:0005524	ATP binding	molecular_function
GO:0008134	transcription factor binding	molecular_function
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	molecular_function
GO:0019902	phosphatase binding	molecular_function
GO:0031435	mitogen-activated protein kinase kinase kinase binding	molecular_function
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