elongator acetyltransferase complex subunit 3

Symbol

ELP3 (may also be known as: None)

Organism

Human

Description

ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009]

Orthologs

SymbolSpecies
elpc-3 Caenorhabditis elegans
Elp3 Drosophila melanogaster
elp3 Danio rerio
Elp3 Mus musculus
Elp3 Rattus norvegicus
ELP3 Saccharomyces cerevisiae
elp3 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2108 elongation protein 3 homolog (S. cerevisiae) decreases with age Molecular ovary Human ELP3 54.1% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006357 regulation of transcription from RNA polymerase II promoter biological_process
GO:0006368 transcription elongation from RNA polymerase II promoter biological_process
GO:0005634 nucleus cellular_component
GO:0005730 nucleolus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0008023 transcription elongation factor complex cellular_component
GO:0016591 DNA-directed RNA polymerase II, holoenzyme cellular_component
GO:0003677 DNA binding molecular_function
GO:0003824 catalytic activity molecular_function
GO:0004402 histone acetyltransferase activity molecular_function
GO:0005515 protein binding molecular_function
GO:0008080 N-acetyltransferase activity molecular_function
GO:0008607 phosphorylase kinase regulator activity molecular_function
GO:0016746 transferase activity, transferring acyl groups molecular_function
GO:0046872 metal ion binding molecular_function
GO:0051536 iron-sulfur cluster binding molecular_function