interleukin 6 (interferon, beta 2)

Symbol

IL6

Organism

Human

Orthologs

SymbolSpecies
Il6 Mus musculus
Il6 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1209 Blood IL6 level increase Physiological plasma Human IL6 —

GO Terms

GO IDGO TermGO Category
GO:0001781 neutrophil apoptosis biological_process
GO:0002384 hepatic immune response biological_process
GO:0002446 neutrophil mediated immunity biological_process
GO:0002548 monocyte chemotaxis biological_process
GO:0002675 positive regulation of acute inflammatory response biological_process
GO:0002690 positive regulation of leukocyte chemotaxis biological_process
GO:0006469 negative regulation of protein kinase activity biological_process
GO:0006953 acute-phase response biological_process
GO:0006954 inflammatory response biological_process
GO:0006955 immune response biological_process
GO:0006959 humoral immune response biological_process
GO:0007568 aging biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0008285 negative regulation of cell proliferation biological_process
GO:0008360 regulation of cell shape biological_process
GO:0009408 response to heat biological_process
GO:0009409 response to cold biological_process
GO:0009611 response to wounding biological_process
GO:0009612 response to mechanical stimulus biological_process
GO:0009617 response to bacterium biological_process
GO:0010574 regulation of vascular endothelial growth factor production biological_process
GO:0010888 negative regulation of lipid storage biological_process
GO:0014070 response to organic cyclic compound biological_process
GO:0016049 cell growth biological_process
GO:0019221 cytokine-mediated signaling pathway biological_process
GO:0030168 platelet activation biological_process
GO:0031000 response to caffeine biological_process
GO:0031018 endocrine pancreas development biological_process
GO:0031175 neuron projection development biological_process
GO:0031667 response to nutrient levels biological_process
GO:0032494 response to peptidoglycan biological_process
GO:0032496 response to lipopolysaccharide biological_process
GO:0032722 positive regulation of chemokine production biological_process
GO:0032755 positive regulation of interleukin-6 production biological_process
GO:0032868 response to insulin stimulus biological_process
GO:0032966 negative regulation of collagen biosynthetic process biological_process
GO:0033138 positive regulation of peptidyl-serine phosphorylation biological_process
GO:0033160 positive regulation of protein import into nucleus, translocation biological_process
GO:0034097 response to cytokine stimulus biological_process
GO:0042102 positive regulation of T cell proliferation biological_process
GO:0042110 T cell activation biological_process
GO:0042493 response to drug biological_process
GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein biological_process
GO:0042832 defense response to protozoan biological_process
GO:0042981 regulation of apoptotic process biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process biological_process
GO:0043200 response to amino acid stimulus biological_process
GO:0043410 positive regulation of MAPKKK cascade biological_process
GO:0043526 neuroprotection biological_process
GO:0045079 negative regulation of chemokine biosynthetic process biological_process
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep biological_process
GO:0045429 positive regulation of nitric oxide biosynthetic process biological_process
GO:0045454 cell redox homeostasis biological_process
GO:0045599 negative regulation of fat cell differentiation biological_process
GO:0045630 positive regulation of T-helper 2 cell differentiation biological_process
GO:0045666 positive regulation of neuron differentiation biological_process
GO:0045669 positive regulation of osteoblast differentiation biological_process
GO:0045721 negative regulation of gluconeogenesis biological_process
GO:0045727 positive regulation of translation biological_process
GO:0045740 positive regulation of DNA replication biological_process
GO:0045765 regulation of angiogenesis biological_process
GO:0045768 positive regulation of anti-apoptosis biological_process
GO:0045893 positive regulation of transcription, DNA-dependent biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter biological_process
GO:0046427 positive regulation of JAK-STAT cascade biological_process
GO:0046677 response to antibiotic biological_process
GO:0046716 muscle cell homeostasis biological_process
GO:0046849 bone remodeling biological_process
GO:0046888 negative regulation of hormone secretion biological_process
GO:0048635 negative regulation of muscle organ development biological_process
GO:0048661 positive regulation of smooth muscle cell proliferation biological_process
GO:0050679 positive regulation of epithelial cell proliferation biological_process
GO:0050710 negative regulation of cytokine secretion biological_process
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation biological_process
GO:0050829 defense response to Gram-negative bacterium biological_process
GO:0050830 defense response to Gram-positive bacterium biological_process
GO:0050871 positive regulation of B cell activation biological_process
GO:0051024 positive regulation of immunoglobulin secretion biological_process
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity biological_process
GO:0051092 positive regulation of NF-kappaB transcription factor activity biological_process
GO:0051384 response to glucocorticoid stimulus biological_process
GO:0051592 response to calcium ion biological_process
GO:0051602 response to electrical stimulus biological_process
GO:0051607 defense response to virus biological_process
GO:0051897 positive regulation of protein kinase B signaling cascade biological_process
GO:0051971 positive regulation of transmission of nerve impulse biological_process
GO:0060445 branching involved in salivary gland morphogenesis biological_process
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis biological_process
GO:0070091 glucagon secretion biological_process
GO:0070102 interleukin-6-mediated signaling pathway biological_process
GO:0070301 cellular response to hydrogen peroxide biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:2000366 positive regulation of STAT protein import into nucleus biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005896 interleukin-6 receptor complex cellular_component
GO:0009897 external side of plasma membrane cellular_component
GO:0005125 cytokine activity molecular_function
GO:0005138 interleukin-6 receptor binding molecular_function
GO:0008083 growth factor activity molecular_function