apolipoprotein E

Symbol

APOE

Organism

Human

Orthologs

Symbol	Species
apoea	Danio rerio
Apoe	Mus musculus
Apoe	Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA1223	APOE promoter methylation decrease	Molecular	prefrontal cortex	Human	APOE	—

First
Last

GO Terms

GO ID	GO Term	GO Category
GO:0000302	response to reactive oxygen species	biological_process
GO:0001937	negative regulation of endothelial cell proliferation	biological_process
GO:0002021	response to dietary excess	biological_process
GO:0006629	lipid metabolic process	biological_process
GO:0006641	triglyceride metabolic process	biological_process
GO:0006707	cholesterol catabolic process	biological_process
GO:0006874	cellular calcium ion homeostasis	biological_process
GO:0006898	receptor-mediated endocytosis	biological_process
GO:0006916	anti-apoptosis	biological_process
GO:0006917	induction of apoptosis	biological_process
GO:0006979	response to oxidative stress	biological_process
GO:0007010	cytoskeleton organization	biological_process
GO:0007186	G-protein coupled receptor signaling pathway	biological_process
GO:0007263	nitric oxide mediated signal transduction	biological_process
GO:0007271	synaptic transmission, cholinergic	biological_process
GO:0007568	aging	biological_process
GO:0008203	cholesterol metabolic process	biological_process
GO:0008219	cell death	biological_process
GO:0010468	regulation of gene expression	biological_process
GO:0010544	negative regulation of platelet activation	biological_process
GO:0010873	positive regulation of cholesterol esterification	biological_process
GO:0010875	positive regulation of cholesterol efflux	biological_process
GO:0014012	peripheral nervous system axon regeneration	biological_process
GO:0019934	cGMP-mediated signaling	biological_process
GO:0030195	negative regulation of blood coagulation	biological_process
GO:0030516	regulation of axon extension	biological_process
GO:0030828	positive regulation of cGMP biosynthetic process	biological_process
GO:0032488	Cdc42 protein signal transduction	biological_process
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	biological_process
GO:0033344	cholesterol efflux	biological_process
GO:0033700	phospholipid efflux	biological_process
GO:0034372	very-low-density lipoprotein particle remodeling	biological_process
GO:0034374	low-density lipoprotein particle remodeling	biological_process
GO:0034375	high-density lipoprotein particle remodeling	biological_process
GO:0034380	high-density lipoprotein particle assembly	biological_process
GO:0034382	chylomicron remnant clearance	biological_process
GO:0034384	high-density lipoprotein particle clearance	biological_process
GO:0034447	very-low-density lipoprotein particle clearance	biological_process
GO:0042157	lipoprotein metabolic process	biological_process
GO:0042158	lipoprotein biosynthetic process	biological_process
GO:0042159	lipoprotein catabolic process	biological_process
GO:0042311	vasodilation	biological_process
GO:0042632	cholesterol homeostasis	biological_process
GO:0043085	positive regulation of catalytic activity	biological_process
GO:0043407	negative regulation of MAP kinase activity	biological_process
GO:0043537	negative regulation of blood vessel endothelial cell migration	biological_process
GO:0043691	reverse cholesterol transport	biological_process
GO:0044281	small molecule metabolic process	biological_process
GO:0045471	response to ethanol	biological_process
GO:0045541	negative regulation of cholesterol biosynthetic process	biological_process
GO:0046907	intracellular transport	biological_process
GO:0048168	regulation of neuronal synaptic plasticity	biological_process
GO:0048844	artery morphogenesis	biological_process
GO:0050728	negative regulation of inflammatory response	biological_process
GO:0051000	positive regulation of nitric-oxide synthase activity	biological_process
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	biological_process
GO:0051651	maintenance of location in cell	biological_process
GO:0055088	lipid homeostasis	biological_process
GO:0071363	cellular response to growth factor stimulus	biological_process
GO:0072358	cardiovascular system development	biological_process
GO:0005576	extracellular region	cellular_component
GO:0005615	extracellular space	cellular_component
GO:0005737	cytoplasm	cellular_component
GO:0005769	early endosome	cellular_component
GO:0005770	late endosome	cellular_component
GO:0005794	Golgi apparatus	cellular_component
GO:0005874	microtubule	cellular_component
GO:0005886	plasma membrane	cellular_component
GO:0030425	dendrite	cellular_component
GO:0031232	extrinsic to external side of plasma membrane	cellular_component
GO:0034361	very-low-density lipoprotein particle	cellular_component
GO:0034362	low-density lipoprotein particle	cellular_component
GO:0034363	intermediate-density lipoprotein particle	cellular_component
GO:0034364	high-density lipoprotein particle	cellular_component
GO:0042627	chylomicron	cellular_component
GO:0043025	neuronal cell body	cellular_component
GO:0001540	beta-amyloid binding	molecular_function
GO:0005319	lipid transporter activity	molecular_function
GO:0005515	protein binding	molecular_function
GO:0005543	phospholipid binding	molecular_function
GO:0008201	heparin binding	molecular_function
GO:0008289	lipid binding	molecular_function
GO:0016209	antioxidant activity	molecular_function
GO:0017127	cholesterol transporter activity	molecular_function
GO:0042802	identical protein binding	molecular_function
GO:0042803	protein homodimerization activity	molecular_function
GO:0046911	metal chelating activity	molecular_function
GO:0046982	protein heterodimerization activity	molecular_function
GO:0048156	tau protein binding	molecular_function
GO:0050750	low-density lipoprotein particle receptor binding	molecular_function
GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity	molecular_function
GO:0070326	very-low-density lipoprotein particle receptor binding	molecular_function
GO:0071813	lipoprotein particle binding	molecular_function
▼ Show more GO terms