Fc fragment of IgG, low affinity IIa, receptor (CD32)
Symbol
FCGR2A
(may also be known as: None)
Organism
Human
Description
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| Fcgr2 | Mus musculus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2271 | Fc fragment of IgG, low affinity IIa, receptor (CD32) increases with age | Molecular | temporal lobe | Human | FCGR2A | 124.0% Increase Gene Expression Level | |
| DAA2277 | Fc fragment of IgG, low affinity IIa, receptor (CD32) increases with age | Molecular | hippocampus | Human | FCGR2A | 316.4% Increase Gene Expression Level | |
| DAA2284 | Fc fragment of IgG, low affinity IIa, receptor (CD32) increases with age | Molecular | parietal lobe | Human | FCGR2A | 141.5% Increase Gene Expression Level | |
| DAA2292 | Fc fragment of IgG, low affinity IIa, receptor (CD32) increases with age | Molecular | frontal lobe | Human | FCGR2A | 104.3% Increase Gene Expression Level |
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0005886 | plasma membrane | cellular_component |
| GO:0016021 | integral to membrane | cellular_component |
| GO:0004872 | receptor activity | molecular_function |
| GO:0019864 | IgG binding | molecular_function |