3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1

Symbol

Hmgcs1 (may also be known as: MGC36662, )

Organism

Mouse

Orthologs

SymbolSpecies
F25B4.6 Caenorhabditis elegans
hmgcs1 Danio rerio
HMGCS1 Homo sapiens
Hmgcs1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1498 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 Molecular kidney Mouse Hmgcs1 4.0% Decrease Gene Expression Level

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3179 Gene expression of HMGCS1 decreases with age Molecular skin Human HMGCS1 —

GO Terms

GO IDGO TermGO Category
GO:0006694 steroid biosynthetic process biological_process
GO:0006695 cholesterol biosynthetic process biological_process
GO:0008152 metabolic process biological_process
GO:0008299 isoprenoid biosynthetic process biological_process
GO:0008610 lipid biosynthetic process biological_process
GO:0010243 response to organic nitrogen biological_process
GO:0016126 sterol biosynthetic process biological_process
GO:0005737 cytoplasm cellular_component
GO:0005829 cytosol cellular_component
GO:0003824 catalytic activity molecular_function
GO:0004421 hydroxymethylglutaryl-CoA synthase activity molecular_function
GO:0008144 drug binding molecular_function
GO:0016740 transferase activity molecular_function
GO:0016853 isomerase activity molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0043177 organic acid binding molecular_function