adaptor-related protein complex 2, sigma 1 subunit
Symbol
AP2S1
(may also be known as: None)
Organism
Human
Description
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Orthologs
| Symbol | Species | |
|---|---|---|
| aps-2 | Caenorhabditis elegans | |
| AP-2sigma | Drosophila melanogaster | |
| ap2s1 | Danio rerio | |
| Ap2s1 | Mus musculus | |
| Ap2s1 | Rattus norvegicus | |
| APS2 | Saccharomyces cerevisiae | |
| aps2 | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006810 | transport | biological_process | |
| GO:0006886 | intracellular protein transport | biological_process | |
| GO:0007173 | epidermal growth factor receptor signaling pathway | biological_process | |
| GO:0007268 | synaptic transmission | biological_process | |
| GO:0007411 | axon guidance | biological_process | |
| GO:0015031 | protein transport | biological_process | |
| ▼ Show more GO terms | |||