MicroRNA let-7b expression upregulated

Molecular

Data Availability

Period at which this change occurs is not accurately known

Tissue

skeletal muscle Changes ⇩
- Anatomical System
  - anatomical site
    - head and neck
    - thorax
      - thoracic wall
    - abdomen
    - pelvis
    - perineum
    - upper limb
    - lower limb
    - whole body
    - adipose tissue
    - mucosa
    - spine
  - cardiovascular system
    - heart
      - atrium
      - ventricle
        
        left ventricle
      - endocardium
      - myocardium
      - pericardium
      - cardiac valve
      - cardiac conducting system
    - artery
      - aorta
      - arterial intima
      - arterial media
      - arterial adventitia
      - carotid artery
      - coronary artery
    - vein
      - venous intima
      - venous media
      - venous adventitia
    - capillary
  - respiratory system
    - nose
    - sinus
    - larynx
    - trachea
    - bronchus
    - lung
      - alveolus
    - pleura
    - diaphragm
  - hematological system
    - bone marrow
      - hematopoietic stem cells
      - mesenchymal stem cell
    - blood
      - plasma
      - myeloid progenitor cell
  - lymphoreticular system
    - lymph
    - lymph node
    - tonsil
    - spleen
  - alimentary system
    - oral cavity
      - tongue
      - salivary gland
      - tooth
      - gum
    - pharynx
      - nasopharynx
      - oropharynx
      - hypopharynx
    - oesophagus
    - stomach
      - gastric mucosa
    - intestine
      - small intestine
        
        duodenum
        
        jejunum
        
        ileum
      - vermiform appendix
      - large intestine
        
        colorectal
        
        colon
        
        appendix
        
        rectum
        
        anus
        
        cecum
    - mesentery
    - omentum
    - peritoneum
    - liver and biliary system
      - liver
      - gall bladder
      - bile duct
    - pancreas
      - exocrine pancreas
  - urogenital system
    - urinary system
      - kidney
        
        nephron
        
        renal corpuscle
        
        glomerus
        
        renal tubule
        
        renal proximal convoluted tubule
        
        renal distal convoluted tubule
        
        loop of Henle
        
        renal collecting duct
        
        renal vasculature
        
        glomerulus
      - ureter
      - bladder
      - urethra
    - reproductive system
      - male reproductive system
        
        testis
        
        seminiferous tubule
        
        epididymis
        
        prostate
        
        vas deferens
        
        penis
        
        glans
        
        foreskin
      - female reproductive system
        
        ovary
        
        uterine tube
        
        uterus
        
        cervix
        
        endometrium
        
        myometrium
        
        vagina
        
        vulva
        
        breast
        
        mammary gland
  - endocrine system
    - endocrine pancreas
      - islets of Langerhans
    - pineal gland
    - pituitary gland
    - thyroid
    - parathyroid
    - adrenal gland
      - adrenal cortex
      - adrenal medulla
  - musculoskeletal system
    - bone
      - ulna
      - femur
    - cartilage
    - joint
      - synovium
      - ligament
      - meniscus
    - muscle
      - skeletal muscle
      - smooth muscle
    - tendon
    - fascia
  - integument system
    - skin
      - epidermis
      - dermis
    - appendages
      - hair follicle
      - hair
      - nail bed
      - nail
      - sweat gland
      - sebaceous gland
    - subcutaneous
  - nervous system
    - central nervous system
      - brain
        
        cerebrum
        
        cerebral cortex
        
        frontal lobe
        
        prefrontal cortex
        
        parietal lobe
        
        temporal lobe
        
        occipital lobe
        
        visual
        
        insula
        
        olfactory bulb
        
        anterior olfactory nucleus
        
        lateral olfactory stria
        
        medial olfactory stria
        
        olfactory tubercle
        
        primary olfactory cortex
        
        secondary olfactory cortex
        
        hippocampus
        
        parahippocampal gyrus
        
        basal nuclei
        
        hypothalamus
        
        preoptic nucleus
        
        supraoptic nucleus
        
        suprachiasmatic nucleus
        
        paraventricular nucleus
        
        infundibular nucleus
        
        anterior nucleus
        
        dorsomedial nucleus
        
        ventromedial nucleus
        
        lateral nucleus
        
        posterior nucleus
        
        premamillary nucleus
        
        tuberomamillary nucleus
        
        medial mamillary nucleus
        
        lateral mamillary nucleus
        
        lateral tuberal nucleus
        
        brain stem
        
        midbrain
        
        crus cerebri
        
        colliculi
        
        substantia nigra
        
        red nucleus
        
        periaqueductal grey matter
        
        oculomotor nucleus
        
        trochlear nucleus
        
        mesencephalic trigeminal nucleus
        
        pons
        
        vestibular nuclei
        
        cochlear nuclei
        
        superior olivary nucleus
        
        trapezoid nucleus
        
        nucleus of the lateral lemniscus
        
        abducent nucleus
        
        facial nucleus
        
        salivatory nuclei
        
        trigeminal nucleus
        
        cerebellum
        
        cerebellum cortex
        
        cerebellum nuclei
        
        tract
        
        corpus callosum
        
        ventricular system
        
        cerebrospinal fluid
        
        meninges
        
        white matter
        
        grey matter
        
        blood brain barrier
      - spinal cord
    - peripheral nervous system
      - visual apparatus
        
        globe
        
        eyelid
        
        lacrimal gland
        
        conjunctiva
        
        cornea
        
        sclera
        
        lens
        
        vitreous humor
        
        iris
        
        ciliary body
        
        choroid
        
        retina
        
        optic nerve
        
        trabecular meshwork
      - auditory apparatus
        
        external ear
        
        middle ear
        
        tympanum
        
        auditory tube
        
        auditory ossicle
        
        internal ear
        
        osseous labyrinth
        
        cochlea
        
        spiral organ of Corti
        
        semicircular canal
        
        vestibule
        
        membranous labyrinth
      - olfactory apparatus
      - peripheral nerve
      - ganglion
      - sympathetic chain
  - immune system
    - thymus
      - T cell progenitor
    - lymphocytes
    - B cell
    - memory B cell
    - T cell
    - T regulatory cell
    - stromal cell
    - naïve T cell
    - neutrophil
    - macrophage
    - natural killer cell
    - dendritic cell
    - leukocyte

References

Drummond et al. (2011) "Aging and microRNA expression in human skeletal muscle: a microarray and bioinformatics analysis." Physiol. Genomics 43(10):595-603 (PubMed)
Other changes View LibAge entry

Referencing provided by LibAge

Description

MicroRNA let-7b is significantly upregulated with age.