Circulating miR-21 expression increases

Molecular

Data Availability

20 to 105 years

Tissue

  • blood Changes

References

  • Olivieri et al. (2012) "Age-related differences in the expression of circulating microRNAs: miR-21 as a new circulating marker of inflammaging." Mech. Ageing Dev. 133(11-12):675-685 (PubMed)
Referencing provided by LibAge

Description

An age-related non-monotonic trend in miR-21 expression was confirmed in both the relative and absolute quantifications. The 66–96 years age group showed significantly higher absolute and relative miR-21 levels than the younger group (20–65 years). The relative expression of miR-21 in centenarians was not significantly different from that in the 20–65 years group, whereas the absolute expression of miR-21 in centenarians was significantly higher than that of the younger 20–65 years group.