| DAA728 |
Brain matter volume declines |
Physiological |
brain |
Human |
— |
— |
|
| DAA733 |
Neurotransmitter and neuro receptor concentrations are altered |
Physiological |
brain |
Human |
— |
— |
|
| DAA779 |
Prefrontal cortex activation during learning is reduced |
Physiological |
brain |
Human |
— |
— |
|
| DAA763 |
Prolongation of calcium signals in nerve cells |
Physiological |
brain |
Human |
— |
— |
|
| DAA784 |
Increased transient activity in non-spatial auditory working memory test |
Physiological |
brain |
Human |
— |
— |
|
| DAA780 |
Medial temporal activation during encoding and retrieval of memory is reduced |
Physiological |
brain |
Human |
— |
— |
|
| DAA732 |
Glial cell number |
Physiological |
cerebral cortex |
Human |
— |
— |
|
| DAA743 |
Sensitivity of HPA axis is impaired |
Physiological |
pituitary gland, adrenal gland, hypothalamus |
Human |
— |
— |
|
| DAA1996 |
Beta-amyloid protein deposition increases |
Physiological |
brain |
Human |
APP |
— |
|
| DAA724 |
Global neuron loss |
Physiological |
cerebral cortex |
Human |
— |
— |
|
| DAA744 |
EEG alterations during auditory test |
Physiological |
brain |
Human |
— |
— |
|
| DAA762 |
Down regulation of calcium clearance from nerve cells |
Physiological |
brain |
Human |
— |
— |
|
| DAA722 |
Accumulation of neuromelanin in dopaminergic nigral neurons |
Physiological |
substantia nigra |
Human |
— |
— |
|
| DAA2037 |
Decrease in mitochondrial content and oxidative metabolism in cells |
Physiological |
brain |
Mouse |
— |
— |
|
| DAA727 |
Axon loss |
Physiological |
white matter |
Human |
— |
— |
|
| DAA726 |
Demyelination |
Physiological |
white matter |
Human |
— |
— |
|
| DAA741 |
Cerebral blood flow and glucose utilization are reduced |
Physiological |
brain |
Human |
— |
— |
|
| DAA740 |
Cortical plasticity decreases |
Physiological |
brain |
Human |
— |
— |
|
| DAA717 |
Dendrite regression, reduction in dendrite length |
Physiological |
brain |
Human |
— |
— |
|
| DAA739 |
Degeneration of dopamine neurons and receptors |
Physiological |
brain |
Human |
— |
— |
|
| DAA787 |
Increased bilateral anterior frontal activity in memory interference tests |
Physiological |
brain |
Human |
— |
— |
|
| DAA738 |
Cerebral spinal fluid amount increases |
Physiological |
brain |
Human |
— |
— |
|
| DAA764 |
Depolarization of mitochondria |
Physiological |
brain |
Human |
— |
— |
|
| DAA1949 |
Intracellular glutathione content decreases |
Physiological |
brain |
Mouse |
— |
— |
|
| DAA1948 |
Neurogenesis is reduced |
Physiological |
brain |
Mouse |
— |
— |
|