DAA921 |
Decrease in melatonin concentration and loss of circadian rhythm for secretion |
Physiological |
plasma, pineal gland |
Human |
— |
— |
|
DAA925 |
Increase in follicle stimulating hormone (FSH) and luteinizing hormone (LH) preceding menopause |
Physiological |
plasma |
Human |
— |
— |
|
DAA928 |
Sex hormone binding globulin levels increase |
Physiological |
plasma |
Human |
— |
— |
|
DAA932 |
Renewal capacity declines |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
DAA933 |
No changes in erythroid and myeloid progenitor cells evident |
Physiological |
myeloid progenitor cell |
Human |
— |
— |
|
DAA934 |
Number of mature B cells leaving the bone marrow declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA936 |
Volume of hematopoietic bone marrow decreases |
Physiological |
bone marrow |
Human |
— |
— |
|
DAA946 |
Thymic hormone levels decrease |
Physiological |
plasma |
Human |
— |
— |
|
DAA968 |
Chronic inflammation increases |
Physiological |
blood, immune system |
Human |
— |
— |
|