| DAA912 |
Aldosterone secretion, blood levels and clearance decrease |
Physiological |
plasma, adrenal gland |
Human |
— |
— |
|
| DAA916 |
Cortisol levels increased |
Physiological |
plasma |
Human |
— |
— |
|
| DAA917 |
Plasma and urinary catecholamine elevation after stimuli |
Physiological |
plasma |
Human |
— |
— |
|
| DAA919 |
Somatostatin basal levels increase |
Physiological |
plasma |
Human |
SST |
— |
|
| DAA92 |
guanine nucleotide binding protein (G protein), beta 5 |
Molecular |
brain |
Human |
GNB5 |
17.0% Decrease Gene Expression Level |
|
| DAA920 |
Prolactin increases in males |
Physiological |
plasma |
Human |
— |
— |
|
| DAA921 |
Decrease in melatonin concentration and loss of circadian rhythm for secretion |
Physiological |
plasma, pineal gland |
Human |
— |
— |
|
| DAA921 |
Decrease in melatonin concentration and loss of circadian rhythm for secretion |
Physiological |
plasma, pineal gland |
Human |
— |
— |
|
| DAA922 |
Deficits in homeostatic equilibrium controlled by endocrine system |
Physiological |
endocrine system |
Human |
— |
— |
|
| DAA923 |
Menopause and female fertility loss |
Physiological |
female reproductive system, endocrine system |
Human |
— |
— |
|
| DAA923 |
Menopause and female fertility loss |
Physiological |
female reproductive system, endocrine system |
Human |
— |
— |
|
| DAA924 |
Decline in ovarian estrogen production |
Physiological |
ovary |
Human |
— |
— |
|
| DAA925 |
Increase in follicle stimulating hormone (FSH) and luteinizing hormone (LH) preceding menopause |
Physiological |
plasma |
Human |
— |
— |
|
| DAA926 |
Hot flushes |
Physiological |
whole body |
Human |
— |
— |
|
| DAA928 |
Sex hormone binding globulin levels increase |
Physiological |
plasma |
Human |
— |
— |
|
| DAA93 |
guanine nucleotide binding protein (G protein), gamma 11 |
Molecular |
brain |
Human |
GNG11 |
23.0% Increase Gene Expression Level |
|
| DAA931 |
Sperm motility and concentration |
Physiological |
male reproductive system |
Human |
— |
— |
|
| DAA932 |
Renewal capacity declines |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
| DAA933 |
No changes in erythroid and myeloid progenitor cells evident |
Physiological |
myeloid progenitor cell |
Human |
— |
— |
|
| DAA934 |
Number of mature B cells leaving the bone marrow declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
| DAA934 |
Number of mature B cells leaving the bone marrow declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
| DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
| DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
| DAA936 |
Volume of hematopoietic bone marrow decreases |
Physiological |
bone marrow |
Human |
— |
— |
|
| DAA939 |
Naive cell number increases and memory cells decrease |
Physiological |
B cell |
Human |
— |
— |
|