deleted in lung and esophageal cancer 1

Symbol

DLEC1 (may also be known as: None)

Organism

Human

Description

This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney. [provided by RefSeq, Jul 2008]

Orthologs

Symbol	Species
dlec1	Danio rerio

Links to external resources

Entrez Gene: 9940
OMIM: 604050
Ensembl: ENSG00000008226
UniProt: Q9Y238
UniGene: Hs.714499
GeneCards

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA3585	Gene expression of DLEC1 increases with age	Molecular	skin	Human	DLEC1	—

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GO Terms

GO ID	GO Term	GO Category
GO:0008285	negative regulation of cell proliferation	biological_process
GO:0005737	cytoplasm	cellular_component
GO:0003674	molecular_function	molecular_function