KIAA0319
Symbol
KIAA0319
(may also be known as: None)
Organism
Human
Description
This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Orthologs
| Symbol | Species | |
|---|---|---|
| uncharacterized_F1RD | Danio rerio | |
| Kiaa0319 | Mus musculus | |
| uncharacterized_P0CI | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0001764 | neuron migration | biological_process | |
| GO:0007275 | multicellular organismal development | biological_process | |
| GO:0007399 | nervous system development | biological_process | |
| GO:2000171 | negative regulation of dendrite development | biological_process | |
| GO:0005769 | early endosome | cellular_component | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0031901 | early endosome membrane | cellular_component | |
| GO:0005515 | protein binding | molecular_function | |