MAD2L1 binding protein

Symbol

MAD2L1BP (may also be known as: None)

Organism

Human

Description

The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
uncharacterized_E7F9 Danio rerio
Mad2l1bp Mus musculus
Mad2l1bp Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2086 MAD2L1 binding protein increases with age Molecular ovary Human MAD2L1BP 58.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0007093 mitotic cell cycle checkpoint biological_process
GO:0007096 regulation of exit from mitosis biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005819 spindle cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005515 protein binding molecular_function