N-myristoyltransferase 2

Symbol

NMT2 (may also be known as: None)

Organism

Human

Description

N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
nmt2 Danio rerio
Nmt2 Mus musculus
Nmt2 Rattus norvegicus
NMT1 Saccharomyces cerevisiae

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2855 Gene expression of NMT2 increases with age Molecular adipose tissue Human NMT2 —

GO Terms

GO IDGO TermGO Category
GO:0006499 N-terminal protein myristoylation biological_process
GO:0009249 protein lipoylation biological_process
GO:0016032 viral reproduction biological_process
GO:0046788 egress of virus within host cell biological_process
GO:0005737 cytoplasm cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0005829 cytosol cellular_component
GO:0005886 plasma membrane cellular_component
GO:0003824 catalytic activity molecular_function
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity molecular_function
GO:0016746 transferase activity, transferring acyl groups molecular_function