interleukin 32

Symbol

IL32 (may also be known as: None)

Organism

Human

Description

This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3537 Gene expression of IL32 decreases with age Molecular skin Human IL32 —

GO Terms

GO IDGO TermGO Category
GO:0006952 defense response biological_process
GO:0006955 immune response biological_process
GO:0007155 cell adhesion biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005125 cytokine activity molecular_function